The nutritional supplement sector has grown steadily in recent years, and 2025 has
been especially decisive: consumers are more demanding, better informed, and
increasingly seek clean, effective, evidence-based formulations.
At Lleó Productos Naturales, as third-party manufacturers, we have
seen first-hand which ingredients have stood out this year — and which will set the
trend for 2026.
If your brand is considering refreshing its catalogue, launching a new line, or
repositioning itself, here we explain which vitamins and minerals you cannot afford to
leave out of your strategy.
What has emerged in 2025?
During 2025, three major movements defined micronutrient demand:
1. The rise of holistic wellbeing
Consumers have moved away from focusing solely on “energy” and “defences”, embracing a global wellness approach that integrates mental health, sleep, immune strength, digestion, and cognitive performance. This has driven:
- The rise of vitamin C as an “everyday essential”.
- The consolidation of nervous-system-supporting minerals such as magnesium in all its forms (glycinate, citrate, threonate).
- B-group vitamins associated with “steady vitality”, less linked to stimulants and more to balance.
2. Supplements for modern life: stress, sleep, and focus
Fast-paced lifestyles have led many consumers to seek micronutrients that promote nervous system regulation, mental clarity, and quality rest:
- B6, B12, and B9 as protagonists in anti-stress formulas.
- Magnesium as the leading mineral of 2025, widely used in products for sleep, muscle relaxation, and emotional balance.
- Zinc and selenium thanks to their link to immune and antioxidant health.
3. Clean label and intelligent formulation
Brands are opting for formulas with less ingredients, but more precise, more bioavailable, and better explained. No more “opaque blends”: consumers want clarity and efficacy.
Essential Vitamins and Minerals for 2026
Based on 2025 trends and projections for 2026, these are the must-have micronutrients for any brand aiming to stay competitive:
1. Vitamin D3 (with K2 as the perfect ally)
Persistent vitamin D deficiency in Europe and its role in energy, mood, immunity, and bone health keep it as a “must”.
- 2026 trend: combining it with K2-MK7 to improve calcium uptake.
2. Magnesium (premium forms)
The mineral par excellence of modern wellbeing.
- Bisglycinate → rest and relaxation
- Threonate → focus and cognitive function
- Citrate → digestive support and anti-stress
3. Complejo vitamínico del grupo B
Highly valued for:
- stable energy
- active metabolism
- balanced nervous system
- cognitive performance
In 2026 we will see more formulas with methylated B vitamins for improved bioavailability.
4. Sustained-release vitamin C
The classic antioxidant vitamin makes a strong comeback thanks to:
- tamponed forms (less acidic)
- prolonged release
- combinations with bioflavonoids
- liposomal formats to prevent oxidation
Trend: positioned as “oxidative stress support”, going beyond immunity.
5. Zinc
Essential for:
- immune system
- skin and hair
- hormonal function
Bisglycinate versions are increasing due to better absorption.
6. Selenium
The perfect partner for vitamin E and antioxidant and anti-ageing formulas.
- Trend: selenium-methionine for its high bioavailability.
7. Well-tolerated iron
Supplements that cause irritation are no longer accepted.
In 2026, iron supplements that will prevail:
- bisglycinate
- microencapsulated formats
- gentle formulas for sensitive stomachs
8. Balanced calcium + magnesium
Beyond bone health, these are now positioned as support for:
- muscular function
- metabolic health
- nervous system balance
Which Micronutrients Are on the Rise for 2026?
1. “Cognitive + mineral” formulations
Magnesium threonate + B complex combos for mental focus.
Formulas for stress and sleep:
- Magnesium bisglycinate
- B6
- Zinc
- Vitamin C
- GABA / botanicals (optional depending on brand)
2. Beauty supplements from inside
The classic combination:
- Zinc
- Selenium
- Vitamin C
- Biotin
3. Formulas targeting hair, skin, and nails will be a strong trend in 2026.
Vitamins and nutrients no longer seen as “seasonal”:
- D3
- Vitamin C
- Zinc
- Selenium
How Lleó Can Help You Launch These Trends
As third-party manufacturers, we:
- Create tailor-made formulas with the vitamin and mineral combinations you want to lead with in your 2026 catalogue.
- Advise you on bioavailability, formats, and compatibility.
- We work with natural, clean-label and high-quality ingredients.
- Offer small initial production runs for testing and gradual scaling.
- Guarantee safe, traceable, certified manufacturing for every batch.
- Provide multiple formats: capsules, sachets, liquids, powders, vials, droppers, sprays, and more.
If we previously discussed some emerging ingredients, we now
go deeper to show how 2026 will be defined by smart micro-supplementation: more thoughtful, cleaner formulas with strategic micronutrients. For any brand seeking differentiation, the vitamins and minerals analysed here will be essential.
At Lleó – Productos Naturales, we are ready to help you develop the formulas that your brand needs to make the most of next year’s trends.
For more information on how Lleó can support you in creating supplements aligned
with today’s market demands, visit our website.
